Synthesis and Characterization of New Biodegradable Injectable Thermosensitive Smart Hydrogels for 5-Fluorouracil Delivery

Synthesis and Characterization of New Biodegradable Injectable Thermosensitive Smart Hydrogels for 5-Fluorouracil Delivery

In this paper, injectable, thermosensitive smart hydrogel local drug delivery systems (LDDSs) releasing the model antitumour drug 5-fluorouracil (5-FU) were developed. The systems were based on biodegradable triblock copolymers synthesized via ring opening polymerization (ROP) of ε-caprolactone (CL)...

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Bibliographic Details
Main Authors: Adam Kasiński, Monika Zielińska-Pisklak, Sebastian Kowalczyk, Andrzej Plichta, Anna Zgadzaj, Ewa Oledzka, Marcin Sobczak
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
biomedical hydrogels
ε-caprolactone and poly(ethylene glycol) copolymers
antitumor drug delivery systems
local drug delivery systems
smart hydrogels
Online Access:https://www.mdpi.com/1422-0067/22/15/8330

Internet

https://www.mdpi.com/1422-0067/22/15/8330

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