JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

<p>Abstract</p> <p>Background</p> <p>White matter injury is the major form of brain damage in very preterm infants. Selective white matter injury in the immature brain can be induced by lipopolysaccharide (LPS)-sensitized hypoxic-ischemia (HI) in the postpartum (P) day...

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Bibliographic Details
Main Authors: Wang Lan-Wan, Tu Yi-Fang, Huang Chao-Ching, Ho Chien-Jung
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Neuroinflammation
Subjects:
Apoptosis
Blood–brain barrier damage
Immature brain
JNK
Microglia
Neuroinflammation
Oligodendrocyte progenitor
Tumor necrosis factor-alpha
White matter injury
Online Access:http://www.jneuroinflammation.com/content/9/1/175

Internet

http://www.jneuroinflammation.com/content/9/1/175

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