On Robust Association Testing for Quantitative Traits and Rare Variants

On Robust Association Testing for Quantitative Traits and Rare Variants

With the advance of sequencing technologies, it has become a routine practice to test for association between a quantitative trait and a set of rare variants (RVs). While a number of RV association tests have been proposed, there is a dearth of studies on the robustness of RV association testing for...

Full description

Bibliographic Details
Main Authors: Peng Wei, Ying Cao, Yiwei Zhang, Zhiyuan Xu, Il-Youp Kwak, Eric Boerwinkle, Wei Pan
Format: Article
Language:English
Published: Oxford University Press 2016-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
SKAT
associate testing
next-generation sequencing
rare variants
robustness
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.035485

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.035485

Similar Items