Protective Effects of N-acetylcysteine Against the Statins Cytotoxicity in Freshly Isolated Rat Hepatocytes

Purpose: Hepatotoxicity is one of the most important side effects of the statins therapy as lipid-lowering agents. However, the mechanism(s) of hepatotoxicity induced by these drugs is not clearly understood yet, and no hepatoprotective agent has been developed against this complication. Methods: T...

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Bibliographic Details
Main Authors: Narges Abdoli, Yadollah Azarmi, Mohammad Ali Eghbal
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2014-05-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:http://journals.tbzmed.ac.ir/APB/Abstract/APB_201_20130907114055