The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans.

The Duffy Antigen Receptor for Chemokines (DARC)-null trait, common among persons of African descent and associated with lower absolute neutrophil counts (ANCs), may be linked to increased risk to certain infections including HIV-1 but the underlying causes are poorly understood. We hypothesized tha...

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Bibliographic Details
Main Authors: Kewreshini K Naidoo, Zesuliwe B Shangase, Tabassum Rashid, Ayanda Ngubane, Nasreen Ismail, Thumbi Ndung'u, Christina F Thobakgale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242448