Does Cytomegalovirus Develop Resistance following Antiviral Prophylaxis and Treatment in Renal Transplant Patients in Kuwait?

The resistance of cytomegalovirus (CMV) to ganciclovir or valganciclovir is a factor in therapeutic failure and disease progression. CMV strains resistant to ganciclovir or valganciclovir have been associated with specific mutations in the UL97 and UL54 genes. Sequencing of both CMV UL97 and UL54 ge...

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Bibliographic Details
Main Authors: Nada Madi, Widad Al-Nakib, Alexander Pacsa
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2011/260561