miR-135b Stimulates Osteosarcoma Recurrence and Lung Metastasis via Notch and Wnt/β-Catenin Signaling

miR-135b Stimulates Osteosarcoma Recurrence and Lung Metastasis via Notch and Wnt/β-Catenin Signaling

Cancer stem cells (CSCs) play an important role in osteosarcoma (OS) metastasis and recurrence, and both Wnt/β-catenin and Notch signaling are essential for the development of the biological traits of CSCs. However, the mechanism that underlies the simultaneous hyperactivation of both Wnt/β-catenin...

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Bibliographic Details
Main Authors: Hua Jin, Song Luo, Yun Wang, Chang Liu, Zhenghao Piao, Meng Xu, Wei Guan, Qing Li, Hua Zou, Qun-You Tan, Zhen-Zhou Yang, Yan Wang, Dong Wang, Cheng-Xiong Xu
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117301944

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http://www.sciencedirect.com/science/article/pii/S2162253117301944

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