Increase of somatic cell mutations in oxidative damage-sensitive drosophila

Increase of somatic cell mutations in oxidative damage-sensitive drosophila

Abstract Background Oxidative damage is an important genotoxic source for almost all organisms. To efficiently detect mutations induced by oxidative damage, we previously developed a urate-null Drosophila strain. Using this Drosophila strain, we showed the mutagenic activity of environmental cigaret...

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Bibliographic Details
Main Authors: Ryota Koike, Tomoyo Uchiyama, Sakae Arimoto-Kobayashi, Keinosuke Okamoto, Tomoe Negishi
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Genes and Environment
Subjects:
Uric acid
Somatic cell mutation
Drosophila
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s41021-017-0090-z

Internet

http://link.springer.com/article/10.1186/s41021-017-0090-z

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