Pathophysiological Aspects of the Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations

Pathophysiological Aspects of the Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations

Abdominal aortic aneurysm (AAA) is a complex degenerative vascular disease, with considerable morbidity and mortality rates among the elderly population. The mortality of AAA is related to aneurysm expansion (the enlargement of the aortic diameter up to 30 mm and above) and the subsequent rupture. T...

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Bibliographic Details
Main Authors: Summerhill Volha I., Sukhorukov Vasily N., Eid Ali H., Nedosugova Ludmila V., Sobenin Igor A., Orekhov Alexander N.
Format: Article
Language:English
Published: De Gruyter 2021-06-01
Series:Biomolecular Concepts
Subjects:
abdominal aortic aneurysm
inflammation
mitochondrial dysfunction
genetic susceptibility
mitochondrial dna
Online Access:https://doi.org/10.1515/bmc-2021-0007

Internet

https://doi.org/10.1515/bmc-2021-0007

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