CD44v8-10 mRNA contained in serum exosomes as a diagnostic marker for docetaxel resistance in prostate cancer patients

Background: Docetaxel is first-line chemotherapy for castration-resistant prostate cancer (CRPC), but most patients acquire docetaxel resistance. CD44 has been shown to be involved in drug resistance of cancers including prostate cancer. We hypothesized that CD44 in serum exosomes could be a diagnos...

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Bibliographic Details
Main Authors: Taku Kato, Kosuke Mizutani, Kyojiro Kawakami, Yasunori Fujita, Hidetoshi Ehara, Masafumi Ito
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020309828