Quantitative not qualitative histology differentiates aneurysmal from nondilated ascending aortas and reveals a net gain of medial components
Abstract Medial degeneration is a common histopathological finding in aortopathy and is considered a mechanism for dilatation. We investigated if medial degeneration is specific for sporadic thoracic aortic aneurysms versus nondilated aortas. Specimens were graded by pathologists, blinded to the cli...
Main Authors: | Sameh Yousef, Nana Matsumoto, Issam Dabe, Makoto Mori, Alden B. Landry, Shin-Rong Lee, Yuki Kawamura, Chen Yang, Guangxin Li, Roland Assi, Prashanth Vallabhajosyula, Arnar Geirsson, Gilbert Moeckel, Jay D. Humphrey, George Tellides |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-92659-1 |
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