Animal models to investigate the pathogenesis of rheumatic heart disease

Animal models to investigate the pathogenesis of rheumatic heart disease

Rheumatic fever (RF) and rheumatic heart disease (RHD) are sequelae of group A streptococcal (GAS) infection. Although an autoimmune process has long been considered to be responsible for the initiation of RF/RHD, it is only in the last few decades that the mechanisms involved in the pathogenesis of...

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Bibliographic Details
Main Authors: Catherine M Rush, Brenda L Govan, Suchandan eSikder, Natasha L Williams, Natkunam eKetheesan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Pediatrics
Subjects:
Inflammation
Rheumatic Fever
Rheumatic Heart Disease
Animal Models
group A streptococcus
autoimmune process
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2014.00116/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fped.2014.00116/full

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