Hypoxia imaging with 18F-FAZA PET/CT predicts radiotherapy response in esophageal adenocarcinoma xenografts

Hypoxia imaging with 18F-FAZA PET/CT predicts radiotherapy response in esophageal adenocarcinoma xenografts

Abstract Background Esophageal cancer is an aggressive disease with poor survival rates. A more patient-tailored approach based on predictive biomarkers could improve outcome. We aimed to predict radiotherapy (RT) response by imaging tumor hypoxia with 18F-FAZA PET/CT in an esophageal adenocarcinoma...

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Bibliographic Details
Main Authors: Elodie Melsens, Elly De Vlieghere, Benedicte Descamps, Christian Vanhove, Ken Kersemans, Filip De Vos, Ingeborg Goethals, Boudewijn Brans, Olivier De Wever, Wim Ceelen, Piet Pattyn
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Radiation Oncology
Subjects:
Radioresistance
18F-FAZA pet/CT
Tumor hypoxia
Predictive biomarker
Esophageal adenocarcinoma xenografts
Nimorazole
Online Access:http://link.springer.com/article/10.1186/s13014-018-0984-3

Internet

http://link.springer.com/article/10.1186/s13014-018-0984-3

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