Bumetanide Suppression of Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy

Bumetanide Suppression of Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy

Aquaporins (AQPs) are involved in hypoxia-induced angiogenesis and retinal damage. Bumetanide is a diuretic agent, Na<sup>+</sup>/K<sup>+</sup>/Cl<sup>&#8722;</sup> cotransporter (NKCC1), and AQP 1&#8722;4 inhibitor. We tested the hypothesis that early pos...

Full description

Bibliographic Details
Main Authors: Sibel Guzel, Charles L. Cai, Taimur Ahmad, Michelle Quan, Gloria B. Valencia, Jacob V. Aranda, Kay D. Beharry
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
angiogenesis
aquaporins
bumetanide
insulin-like growth factor-i
intermittent hypoxia
retina
vascular endothelial growth factor
Online Access:https://www.mdpi.com/1422-0067/21/3/987

Internet

https://www.mdpi.com/1422-0067/21/3/987

Similar Items