Epidermal growth factor signalling controls myosin II planar polarity to orchestrate convergent extension movements during Drosophila tubulogenesis.

Most epithelial tubes arise as small buds and elongate by regulated morphogenetic processes including oriented cell division, cell rearrangements, and changes in cell shape. Through live analysis of Drosophila renal tubule morphogenesis we show that tissue elongation results from polarised cell inte...

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Bibliographic Details
Main Authors: Aditya Saxena, Barry Denholm, Stephanie Bunt, Marcus Bischoff, Krishnaswamy VijayRaghavan, Helen Skaer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4251826?pdf=render