Effects of TMK-688 a potent 5-lipoxygenase inhibitor, on dual-phase asthmatic response in conscious guinea pigs sensitized with ovalbumin
We evaluated the anti-asthmatic effects and mechanism of action of TMK-688, a potent 5-lipoxygenase inhibitor, on the dual-phase asthmatic response and on airway inflammation in conscious guinea pigs sensitized with ovalbumin (OA). TMK-688 inhibited both the immediate and the late asthmatic response...
Main Authors: | Yuji Tohda, Masato Muraki, Hirokazu Kubo, Shigenori Nakajima |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1997-01-01
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Series: | Allergology International |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015315872 |
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