Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists

Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists

The follicle-stimulating hormone receptor (FSHR) has been targeted therapeutically for decades, due to its pivotal role in reproduction. To date, only purified and recombinant/biosimilar FSH have been used to target FSHR in assisted reproduction, with the exception of corifollitropin alfa; a modifie...

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Bibliographic Details
Main Authors: Ross C. Anderson, Claire L. Newton, Robert P. Millar
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Endocrinology
Subjects:
follicle-stimulating hormone (FSH)
FSH receptor (FSHR)
agonists
antagonists
small-molecule
GPCR (G protein-coupled receptors)
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00757/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00757/full

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