Selective recruitment of nuclear factors to productively replicating herpes simplex virus genomes.

Much of the HSV-1 life cycle is carried out in the cell nucleus, including the expression, replication, repair, and packaging of viral genomes. Viral proteins, as well as cellular factors, play essential roles in these processes. Isolation of proteins on nascent DNA (iPOND) was developed to label an...

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Bibliographic Details
Main Authors: Jill A Dembowski, Neal A DeLuca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4446364?pdf=render