Generation of "virtual" control groups for single arm prostate cancer adjuvant trials.

Generation of "virtual" control groups for single arm prostate cancer adjuvant trials.

It is difficult to construct a control group for trials of adjuvant therapy (Rx) of prostate cancer after radical prostatectomy (RP) due to ethical issues and patient acceptance. We utilized 8 curve-fitting models to estimate the time to 60%, 65%, … 95% chance of progression free survival (PFS) base...

Full description

Bibliographic Details
Main Authors: Zhenyu Jia, Michael B Lilly, James A Koziol, Xin Chen, Xiao-Qin Xia, Yipeng Wang, Douglas Skarecky, Manuel Sutton, Anne Sawyers, Herbert Ruckle, Philip M Carpenter, Jessica Wang-Rodriguez, Jun Jiang, Mingsen Deng, Cong Pan, Jian-Guo Zhu, Christine E McLaren, Michael J Gurley, Chung Lee, Michael McClelland, Thomas Ahlering, Michael W Kattan, Dan Mercola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3897405?pdf=render

Internet

http://europepmc.org/articles/PMC3897405?pdf=render

Similar Items