In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors

In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors

Abstract Background Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with gout and many life style related diso...

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Bibliographic Details
Main Authors: Neelam Malik, Priyanka Dhiman, Anurag Khatkar
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Chemistry
Subjects:
Hesperitin
Xanthine oxidase
Molecular docking
Antioxidant
Online Access:http://link.springer.com/article/10.1186/s13065-019-0571-1

Internet

http://link.springer.com/article/10.1186/s13065-019-0571-1

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