Role of Prefrontal Cortex Anti- and Pro-inflammatory Cytokines in the Development of Abnormal Behaviors Induced by Disconnection of the Ventral Hippocampus in Neonate Rats

Role of Prefrontal Cortex Anti- and Pro-inflammatory Cytokines in the Development of Abnormal Behaviors Induced by Disconnection of the Ventral Hippocampus in Neonate Rats

Neonatal disconnection of ventral hippocampus (VH) outputs in rats has been reported to lead to post-pubertal behavioral and synaptic changes of relevance to schizophrenia. Increased oxidative and inflammatory load in the prefrontal cortex (PFC) has been suggested to mediate some of the effects of n...

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Bibliographic Details
Main Authors: Antoneta T. Joseph, Sanjeev K. Bhardwaj, Lalit K. Srivastava
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Cytokines
TGF-β1
schizophrenia
animal model
ventral hippocampus
behavior
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2018.00244/full

Internet

https://www.frontiersin.org/article/10.3389/fnbeh.2018.00244/full

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