Genetic modifiers of MeCP2 function in Drosophila.

Genetic modifiers of MeCP2 function in Drosophila.

The levels of methyl-CpG-binding protein 2 (MeCP2) are critical for normal post-natal development and function of the nervous system. Loss of function of MeCP2, a transcriptional regulator involved in chromatin remodeling, causes classic Rett syndrome (RTT) as well as other related conditions charac...

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Bibliographic Details
Main Authors: Holly N Cukier, Alma M Perez, Ann L Collins, Zhaolan Zhou, Huda Y Zoghbi, Juan Botas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2518867?pdf=render

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