Genetic modifiers of MeCP2 function in Drosophila.
The levels of methyl-CpG-binding protein 2 (MeCP2) are critical for normal post-natal development and function of the nervous system. Loss of function of MeCP2, a transcriptional regulator involved in chromatin remodeling, causes classic Rett syndrome (RTT) as well as other related conditions charac...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-09-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2518867?pdf=render |