Base-calling algorithm with vocabulary (BCV) method for analyzing population sequencing chromatograms.

Sanger sequencing is a common method of reading DNA sequences. It is less expensive than high-throughput methods, and it is appropriate for numerous applications including molecular diagnostics. However, sequencing mixtures of similar DNA of pathogens with this method is challenging. This is importa...

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Bibliographic Details
Main Authors: Yuri S Fantin, Alexey D Neverov, Alexander V Favorov, Maria V Alvarez-Figueroa, Svetlana I Braslavskaya, Maria A Gordukova, Inga V Karandashova, Konstantin V Kuleshov, Anna I Myznikova, Maya S Polishchuk, Denis A Reshetov, Yana A Voiciehovskaya, Andrei A Mironov, Vladimir P Chulanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3557274?pdf=render