CSB ablation induced apoptosis is mediated by increased endoplasmic reticulum stress response.

CSB ablation induced apoptosis is mediated by increased endoplasmic reticulum stress response.

The DNA repair protein Cockayne syndrome group B (CSB) has been recently identified as a promising anticancer target. Suppression, by antisense technology, of this protein causes devastating effects on tumor cells viability, through a massive induction of apoptosis, while being non-toxic to non-tran...

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Bibliographic Details
Main Authors: Manuela Caputo, Alessio Balzerano, Ivan Arisi, Mara D'Onofrio, Rossella Brandi, Silvia Bongiorni, Stefano Brancorsini, Mattia Frontini, Luca Proietti-De-Santis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333825?pdf=render

Internet

http://europepmc.org/articles/PMC5333825?pdf=render

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