Establishment and Application of Engineered NIH 3T3 Cell Line with Stable Human RAGE Expression

Aim NIH3T3 cell line with expression of human receptor for advanced glycation end-products (hRAGE) transduced with lentivirus vectors was used to analyze affinity, biological activity, and/or molecular mechanisms of molecules targeting the hRAGE pathway. Method The DNA fragment coding for...

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Bibliographic Details
Main Authors: Xinyi Xiao, Hui Chen, Pameila Paerhati, Meiqi Zhou, Zhuoyi Yang, Siyi Bai, Yunsheng Yuan
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2020-03-01
Series:Pharmaceutical Fronts
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1708511