Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the <i>JMJD6</i> Regulon in Clinical Prostate Cancer

Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the <i>JMJD6</i> Regulon in Clinical Prostate Cancer

Background: Prostate cancer (PCa) is the second most common tumour diagnosed in men. Tumoral heterogeneity in PCa creates a significant challenge to develop robust prognostic markers and novel targets for therapy. An analysis of gene regulatory networks (GRNs) in PCa may provide insight into progres...

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Bibliographic Details
Main Authors: Mario Cangiano, Magda Grudniewska, Mark J. Salji, Matti Nykter, Guido Jenster, Alfonso Urbanucci, Zoraide Granchi, Bart Janssen, Graham Hamilton, Hing Y. Leung, Inès J. Beumer
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
prostate cancer
prognostic biomarkers
gene regulatory network
regulon
transcriptional regulator
Online Access:https://www.mdpi.com/2072-6694/13/9/2094

Internet

https://www.mdpi.com/2072-6694/13/9/2094

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