The effects of immune protein CD3ζ development and degeneration of retinal neurons after optic nerve injury.

Major histocompatibility complex (MHC) class I molecules and their receptors play fundamental roles in neuronal death during diseases. T-cell receptors (TCR) function as MHCI receptor on T-cells and both MHCI and a key component of TCR, CD3ζ, are expressed by mouse retinal ganglion cells (RGCs) and...

Full description

Bibliographic Details
Main Authors: Tao He, Xavier Mortensen, Ping Wang, Ning Tian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5404868?pdf=render