Angiotensin II type 2 receptor signaling affects dopamine levels in the brain and prevents binge eating disorder

Introduction: Binge eating disorder (BED) is associated with dopaminergic activation as food reward, resulting in metabolism-related disorders. Stimulation of angiotensin type 2 (AT 2 ) receptor is reported to inhibit dopamine synthesis. We investigated the possible roles of AT 2 receptor-mediated d...

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Bibliographic Details
Main Authors: Hirotomo Nakaoka, Masaki Mogi, Harumi Kan-no, Kana Tsukuda, Kousei Ohshima, Xiao-Li Wang, Toshiyuki Chisaka, Hui-Yu Bai, Bao-Shuai Shan, Masayoshi Kukida, Jun Iwanami, Masatsugu Horiuchi
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320315573680