A Workflow towards the Reproducible Identification and Quantitation of Protein Carbonylation Sites in Human Plasma

A Workflow towards the Reproducible Identification and Quantitation of Protein Carbonylation Sites in Human Plasma

Protein carbonylation, a marker of excessive oxidative stress, has been studied in the context of multiple human diseases related to oxidative stress. The variety of post-translational carbonyl modifications (carbonyl PTMs) and their low concentrations in plasma challenge their reproducible identifi...

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Bibliographic Details
Main Authors: Juan Camilo Rojas Echeverri, Sanja Milkovska-Stamenova, Ralf Hoffmann
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Antioxidants
Subjects:
protein carbonylation
human plasma
aldehyde reactive probe (ARP)
biotin-avidin affinity
LC-MS/MS
Online Access:https://www.mdpi.com/2076-3921/10/3/369

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https://www.mdpi.com/2076-3921/10/3/369

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