CD8<sup>+ </sup>T cell activation predominate early immune responses to hypercholesterolemia in <it>Apoe</it><sup>-/- </sup>mice

<p>Abstract</p> <p>Background</p> <p>It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully characterized. In the present study we a...

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Bibliographic Details
Main Authors: Björkbacka Harry, Wigren Maria, Persson Josefin, Berg Katarina E, Ramos Ornélia H, Kolbus Daniel, Fredrikson Gunilla, Nilsson Jan
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/11/58