Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults

Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults

Background: T-cell responses against highly conserved influenza antigens have been previously associated with protection. However, these immune responses are poorly maintained following recovery from influenza infection and are not boosted by inactivated influenza vaccines. We have previously demons...

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Bibliographic Details
Main Authors: L. Coughlan, S. Sridhar, R. Payne, M. Edmans, A. Milicic, N. Venkatraman, B. Lugonja, L. Clifton, C. Qi, P.M. Folegatti, A.M. Lawrie, R. Roberts, H. de Graaf, P. Sukhtankar, S.N. Faust, D.J.M. Lewis, T. Lambe, AVS Hill, S.C. Gilbert
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418300653

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http://www.sciencedirect.com/science/article/pii/S2352396418300653

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