Coelimycin Synthesis Activatory Proteins Are Key Regulators of Specialized Metabolism and Precursor Flux in Streptomyces coelicolor A3(2)

Coelimycin Synthesis Activatory Proteins Are Key Regulators of Specialized Metabolism and Precursor Flux in Streptomyces coelicolor A3(2)

Many microbial specialized metabolites are industrially relevant agents but also serve as signaling molecules in intra-species and even inter-kingdom interactions. In the antibiotic-producing Streptomyces, members of the SARP (Streptomyces antibiotic regulatory proteins) family of regulators are oft...

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Bibliographic Details
Main Authors: Bartosz Bednarz, Aaron Millan-Oropeza, Magdalena Kotowska, Michał Świat, Juan J. Quispe Haro, Céline Henry, Krzysztof Pawlik
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
SARP
antibiotic biosynthesis
specialized metabolites
secondary metabolism
precursor flux
dormancy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.616050/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.616050/full

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