MiR-203a-3p regulates the biological behaviors of ovarian cancer cells through mediating the Akt/GSK-3β/Snail signaling pathway by targeting ATM

MiR-203a-3p regulates the biological behaviors of ovarian cancer cells through mediating the Akt/GSK-3β/Snail signaling pathway by targeting ATM

Abstract Objective To investigate whether miR-203a-3p can regulate the biological behaviors of ovarian cancer cells by targeting ATM to affect the Akt/GSK-3β/Snail signaling pathway. Methods The expression levels of miR-203a-3p and ATM were detected by qRT-PCR, immunohistochemical staining and Weste...

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Bibliographic Details
Main Authors: Hong-Yun Liu, Yu-Ying Zhang, Bao-Lian Zhu, Fu-Zhong Feng, Hai-Tang Zhang, Hua Yan, Bin Zhou
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
miR-203a-3p
ATM
Akt/GSK-3β/snail
Online Access:http://link.springer.com/article/10.1186/s13048-019-0532-2

Internet

http://link.springer.com/article/10.1186/s13048-019-0532-2

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