Lower ADD1 gene promoter DNA methylation increases the risk of essential hypertension.

Lower ADD1 gene promoter DNA methylation increases the risk of essential hypertension.

The goal of our study is to investigate the contribution of promoter DNA methylation of α-adducin (ADD1) gene to the risk of essential hypertension (EH). Using the bisulphite pyrosequencing technology, DNA methylation levels of five CpG dinucleotides on ADD1 promoter were measured among 33 EH cases...

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Bibliographic Details
Main Authors: Li-Na Zhang, Pan-Pan Liu, Lingyan Wang, Fang Yuan, Leiting Xu, Yanfei Xin, Li-Juan Fei, Qi-Long Zhong, Yi Huang, Limin Xu, Ling-Mei Hao, Xu-Jun Qiu, Yanping Le, Meng Ye, Shiwei Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3655193?pdf=render

Internet

http://europepmc.org/articles/PMC3655193?pdf=render

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