Chloroquine prophylaxis associated with high prevalence of Plasmodium falciparum Pfcrt K76T mutation in people with sickle-cell disease in Benin City, Nigeria

Background & objectives: High mortality and morbidity in sickle-cell disease has been associated with malaria infection especially in countries where chloroquine is used. Chloroquine resistance has been associated with the emergence of Pfcrt mutant genes. This study aimed at comparing the preva...

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Bibliographic Details
Main Authors: Y.M. Tatfeng, D.E. Agbonlahor, K.S. Tchounga, P.I. Omolu, M. Okodua, C.S. Yah, A. Adeolu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2008-02-01
Series:Journal of Vector Borne Diseases
Subjects:
Online Access:http://www.mrcindia.org/journal/issues/451051.pdf