Using a Two-Sample Mendelian Randomization Method in Assessing the Causal Relationships Between Human Blood Metabolites and Heart Failure

Using a Two-Sample Mendelian Randomization Method in Assessing the Causal Relationships Between Human Blood Metabolites and Heart Failure

Background: Heart failure (HF) is the main cause of morbidity and mortality worldwide, and metabolic dysfunction is an important factor related to HF pathogenesis and development. However, the causal effect of blood metabolites on HF remains unclear.Objectives: Our chief aim is to investigate the ca...

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Bibliographic Details
Main Authors: Zixian Wang, Shiyu Chen, Qian Zhu, Yonglin Wu, Guifeng Xu, Gongjie Guo, Weihua Lai, Jiyan Chen, Shilong Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
heart failure
blood metabolites
Mendelian randomization
4-vinylphenol sulfate
causal relationship
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.695480/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.695480/full

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