A Crucial Role for Ergosterol in Plasma Membrane Composition, Localisation, and Activity of Cdr1p and H<sup>+</sup>-ATPase in <i>Candida albicans</i>

<i>Candida albicans</i> is an opportunistic fungal pathogen of humans. Treatment of <i>C. albicans</i> infections relies on azoles, which target the lanosterol 14&#945;-demethylase (Erg11p) encoded by the <i>ERG11</i> gene. Our results show that targeted gene...

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Bibliographic Details
Main Authors: Jakub Suchodolski, Jakub Muraszko, Przemysław Bernat, Anna Krasowska
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/7/10/378