Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers

Longitudinal structural gray matter and white matter MRI changes in presymptomatic progranulin mutation carriers

Introduction: Mutations in the progranulin (GRN) gene are a major source of inherited frontotemporal degeneration (FTD) spectrum disorders associated with TDP-43 proteinopathy. We use structural MRI to identify regions of baseline differences and longitudinal changes in gray matter (GM) and white ma...

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Bibliographic Details
Main Authors: Christopher A. Olm, Corey T. McMillan, David J. Irwin, Vivianna M. Van Deerlin, Philip A. Cook, James C. Gee, Murray Grossman
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158218301633

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http://www.sciencedirect.com/science/article/pii/S2213158218301633

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