Methamphetamine induces dopamine D1 receptor-dependent endoplasmic reticulum stress-related molecular events in the rat striatum.

Methamphetamine induces dopamine D1 receptor-dependent endoplasmic reticulum stress-related molecular events in the rat striatum.

Methamphetamine (METH) is an illicit toxic psychostimulant which is widely abused. Its toxic effects depend on the release of excessive levels of dopamine (DA) that activates striatal DA receptors. Inhibition of DA-mediated neurotransmission by the DA D1 receptor antagonist, SCH23390, protects again...

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Bibliographic Details
Main Authors: Subramaniam Jayanthi, Michael T McCoy, Genevieve Beauvais, Bruce Ladenheim, Kristi Gilmore, William Wood, Kevin Becker, Jean Lud Cadet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2699544?pdf=render

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http://europepmc.org/articles/PMC2699544?pdf=render

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