OMICs approaches-assisted identification of macrophages-derived MIP-1γ as the therapeutic target of botanical products TNTL in diabetic retinopathy

OMICs approaches-assisted identification of macrophages-derived MIP-1γ as the therapeutic target of botanical products TNTL in diabetic retinopathy

Abstract Background Inflammatory reaction in the dysfunction of retinal endotheliocytes has been considered to play a vital role in diabetic retinopathy (DR). Anti-inflammatory therapy so far gains poor outcome as DR treatment. This study aims to identify a novel therapeutic target of DR from the OM...

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Bibliographic Details
Main Authors: Ning Wang, Cheng Zhang, Yu Xu, Sha Li, Hor-Yue Tan, Wen Xia, Yibin Feng
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Cell Communication and Signaling
Subjects:
Tang-Ning-Tong-Luo
Diabetic retinopathy
Inflammation
Endothelial dysfunctions
MIP1γ/CCR1 axis
Retina macrophages
Online Access:http://link.springer.com/article/10.1186/s12964-019-0396-5

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http://link.springer.com/article/10.1186/s12964-019-0396-5

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