Enhanced Ovarian Cancer Tumorigenesis and Metastasis by the Macrophage Colony-Stimulating Factor

Coexpression of the macrophage colony-stimulating factor (CSF-1) and its receptor (CSF-1R) in metastatic ovarian cancer specimens is a predictor of poor outcome in epithelial ovarian cancer. This suggests that an autocrine loop is produced by which ovarian tumors can secrete CSF-1 stimulating the C...

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Bibliographic Details
Main Authors: Eugene P. Toy, Masoud Azodi, Nancy L. Folk, Christina M. Zito, Caroline J. Zeiss, Setsuko K. Chambers
Format: Article
Language:English
Published: Elsevier 2009-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800262