EGF-mediated EGFR/ERK signaling pathway promotes germinative cell proliferation in Echinococcus multilocularis that contributes to larval growth and development.

EGF-mediated EGFR/ERK signaling pathway promotes germinative cell proliferation in Echinococcus multilocularis that contributes to larval growth and development.

BACKGROUND:Larvae of the tapeworm E. multilocularis cause alveolar echinococcosis (AE), one of the most lethal helminthic infections in humans. A population of stem cell-like cells, the germinative cells, is considered to drive the larval growth and development within the host. The molecular mechani...

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Bibliographic Details
Main Authors: Zhe Cheng, Fan Liu, Xiu Li, Mengya Dai, Jianjian Wu, Xinrui Guo, Huimin Tian, Zhijie Heng, Ying Lu, Xiaoli Chai, Yanhai Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5344531?pdf=render

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http://europepmc.org/articles/PMC5344531?pdf=render

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