Iguratimod: Novel Molecular Insights and a New csDMARD for Rheumatoid Arthritis, from Japan to the World

Iguratimod (IGU) is a conventional synthetic disease-modifying anti-rheumatic drug (csDMARD) routinely prescribed in Japan since 2012 to patients with rheumatoid arthritis (RA). Iguratimod acts directly on B cells by inhibiting the production of inflammatory cytokines (tumor necrosis factor-α, inter...

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Bibliographic Details
Main Author: Yuji Nozaki
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/5/457