Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer
<p>Abstract</p> <p>Background</p> <p>Aurora B kinase is an important mitotic kinase involved in chromosome segregation and cytokinesis. It is overexpressed in many cancers and thus may be an important molecular target for chemotherapy. AZD1152 is the prodrug for AZD1152...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-02-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/42 |