Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer

<p>Abstract</p> <p>Background</p> <p>Aurora B kinase is an important mitotic kinase involved in chromosome segregation and cytokinesis. It is overexpressed in many cancers and thus may be an important molecular target for chemotherapy. AZD1152 is the prodrug for AZD1152...

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Bibliographic Details
Main Authors: Velazquez-Torres Guermarie, Yeung James A, Chen Jian, Zhang Fanmao, Gully Christopher P, Wang Edward, Yeung Sai-Ching, Lee Mong-Hong
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/42