Interleukin-10 reorganizes the cytoskeleton of mature dendritic cells leading to their impaired biophysical properties and motilities.

Interlukin-10 (IL-10) is an immunomodulatory cytokine which predominantly induces immune-tolerance. It has been also identified as a major cytokine in the tumor microenvironment that markedly mediates tumor immune escape. Previous studies on the roles of IL-10 in tumor immunosuppression mainly focus...

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Bibliographic Details
Main Authors: Xiaoli Xu, Xianmei Liu, Jinhua Long, Zuquan Hu, Qinni Zheng, Chunlin Zhang, Long Li, Yun Wang, Yi Jia, Wei Qiu, Jing Zhou, Weijuan Yao, Zhu Zeng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5325303?pdf=render