Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in Caenorhabditis elegans.

Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in Caenorhabditis elegans.

Exposure to diethylhexyl phthalate (DEHP), the most abundant plasticizer used in the production of polyvinyl-containing plastics, has been associated to adverse reproductive health outcomes in both males and females. While the effects of DEHP on reproductive health have been widely investigated, the...

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Bibliographic Details
Main Authors: Luciann Cuenca, Nara Shin, Laura I Lascarez-Lagunas, Marina Martinez-Garcia, Saravanapriah Nadarajan, Rajendiran Karthikraj, Kurunthachalam Kannan, Mónica P Colaiácovo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008529

Internet

https://doi.org/10.1371/journal.pgen.1008529

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