Renal function as a predicting model for plasma methotrexate concentration after high-dose methotrexate chemotherapy in pediatric malignancy
Introduction: Methotrexate (MTX) is the most generally administered antimetabolite in pediatric cancers. Renal excretion is the major route of elimination of MTX. However, renal toxicity and delayed MTX elimination is a particular concern and direct serum MTX concentration is a gold standard for ren...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Society of Diabetic Nephropathy Prevention
2018-05-01
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| Series: | Journal of Nephropharmacology |
| Subjects: | |
| Online Access: | http://jnephropharmacology.com/PDF/npj-7-74.pdf |