Melatonin modifies SOX2+ cell proliferation in dentate gyrus and modulates SIRT1 and MECP2 in long-term sleep deprivation

Melatonin modifies SOX2+ cell proliferation in dentate gyrus and modulates SIRT1 and MECP2 in long-term sleep deprivation

Melatonin is a pleiotropic molecule that, after a short-term sleep deprivation, promotes the proliferation of neural stem cells in the adult hippocampus. However, this effect has not been observed in long-term sleep deprivation. The precise mechanism exerted by melatonin on the modulation of neural...

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Bibliographic Details
Main Authors: Alan Hinojosa-Godinez, Luis F Jave-Suarez, Mario Flores-Soto, Alma Y Gálvez-Contreras, Sonia Luquín, Edith Oregon-Romero, Oscar González-Pérez, Rocio E González-Castañeda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
sleep-deprivation; melatonin; microRNA; neurogenesis; Sirtuin 1; SIRT1; methyl-CpG-binding protein 2; MECP2; epigenetic; text-mining; mir-9; let-7b
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=10;spage=1787;epage=1795;aulast=Hinojosa-Godinez

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=10;spage=1787;epage=1795;aulast=Hinojosa-Godinez

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