When is it rational to participate in a clinical trial? A game theory approach incorporating trust, regret and guilt

<p>Abstract</p> <p>Background</p> <p>Randomized controlled trials (RCTs) remain an indispensable form of human experimentation as a vehicle for discovery of new treatments. However, since their inception RCTs have raised ethical concerns. The ethical tension has revolve...

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Bibliographic Details
Main Authors: Djulbegovic Benjamin, Hozo Iztok
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/12/85